Chemistry and Biochemistry


HOME             DAVID            PUBLICATIONS            MEMBERS  

Independent Publications:

30. Ence, C. C.; Nazari, S. H.; Rodriguez, M.; Kulka, S.; Gassaway, K.; Valdivia-Berroeta, G. A.; Michaelis, D. J. “2-Phosphinoimidazole-Derived Pd(I) and Pd(II) Dimers Enable a Bimetallic Approach to 1,3-Disubstituted Naphthalenes via Tandem Ketone Arylation and Cyclization.” Manuscript in preparation.

29. Martinez, E. E.; Jensen, C. A.; Larson, A. J. S.; Kenney, K. C.; Clark, K. J.; Nazari, S. H.; Valdivia-Berroeta, G. A.; Smith, S. J.; Ess, D. H.; Michaelis, D. J.; “Monosubstituted, Anionic Imidazolyl Ligands from N–H NHC Precursors and Their Activity in Pd-Catalyzed Cross-Coupling Reactions.” Adv. Synth. Catal. 2020, in Press.

28. Bahr, C. B.; Green, N. K.; Heki, L. K.; McMurray, E.; Tangen, I. C.; Valdivia-Berroeta, G. A.; Jackson, E. W.; Michaelis, D. J.; Johnson, J. A. “Heterogeneous layered structures for improved terahertz generation.” Opt. Lett. 2020, 45, 2054-2057.

27. Asay, S.; Graham, A.; Hollingsworth, S.; Barnes, B.; Oblad, R.; Michaelis, D. J.; Kenealey, J. “γ-tocotrienol and ɑ-tocopherol ether acetate enhance docetaxel activity in drug-resistant prostate cancer cells. Molecules 2020, 25, 398.

26. Valdivia-Berroeta, G. A.; Jackson, E. W.; Kenney, K. C.; Wayment, A. X.; Tangen, I. C.; Bahr, C. B.; Smith, S. J.; Michaelis, D. J.; Johnson, J. A. “Designing Non‐Centrosymmetric Molecular Crystals: Optimal Packing May Be Just One Carbon Away.” Adv. Funct. Mat. 2020, 30, 1904786.

25. Nazari, S. H.; Forson, K. G.; Martinez, E. E.; Hansen, N. J.; Gassaway, K. J.; Lyons, N. M.; Kenney, K. C.; Valdivia-Berroeta, G. A.; Smith, S. J.; Michaelis, D. J. “Boron-Templated Dimerization of Allylic Alcohols To Form Protected 1,3-Diols via Acid Catalysis.” Org. Lett. 201921, 9589–9593.

24. Ence, C.; Walker, W. K.; Martinez, E.; Stokes, R. W.; Sarager, S.; Smith, S. J.; Michaelis, D. J. “Synthesis of Chiral Titanium-Containing Ligands for Enantioselective Heterobimetallic Catalysis.”Tetrahedron, 2019, 75, 3341–3347. Tetrahedron Young Investigator Award 2019, A Special Issue in Honor of Professor Ryan Shenvi.

23. Valdivia-Berroeta, G. A.; Hekia, L. K.; Jackson, E. W.; Tangen, I. C.; Bahr, C. B.; Smith, S. J.; Michaelis, d. J.; Johnson, J. A. “Terahertz generation and optical characteristics of (E)-2-(4-(dimethylamino)styryl)-1,1,3-trimethyl-1H-benzo[e]indol-3-ium iodide (P-BI).”Opt. Lett. 2019 44, 4279–4282.

22. Mohl, G.; Liddle, N.; Nygaard, J.; Dorius, A.; Lyons, N.; Hodek, J. Weber, J.; Michaelis, D. J.; Busath, D. D. “Novel Influenza Inhibitors Designed to Target PB1 Interactions with Host Importin RanBP5.” Antiviral Res. 2019, 164, 81–90.

21. Nazari, S. H.; Tiempos-Flores, N.; Forson, K. G.; Bourdeau, J. E.; Michaelis, D. J. “C–N Bond Formation from Allylic Alcohols Via Cooperative Nickel and Titanium Catalysis.” J. Org. Chem. 2018, 83, 10646–10654.


20. Valdivia-Berroeta, G. A.; Heki, L. K.; McMurray, E. A.; Foote, L. A.; Nazari, H. S.; Serafin, L.; Smith, S. J.; Michaelis, D. J.; Johnson, J. A. “Alkynyl Pyridinium Crystals for THz Generation.” Adv. Opt. Mater.2018, 6, 1800383.

19. Nazari, S. H.; Bourdeau, J. E.; Talley, M. R.; Valdivia-Berroeta, G. A.; Smith, S. J.; Michaelis, D. J. “Nickel-Catalyzed Suzuki Cross Couplings with Unprotected Allylic Alcohols Enabled by Bidentate NHC/Phosphine Ligands.” ACS Catal. 2018, 8, 86–89.


18. Kinghorn, M. J.; Valdivia Berroeta, G. A.; Chantry, D. R.; Draper, S. R. E.; Duval, J. S.; Masino, B. M.; Cahoon, S. B.; Flansburg, R. R.; Conder, C. J.; Smith, M. S.; Price, J. L.; Michaelis, D. J. “Proximity-Induced Reactivity and Selectivity with a Rationally De-signed Bifunctional Helical Peptide Catalyst.” Submitted.


17. Tyler, J. H.; Patterson, R. H.; Nazari, S. H.; Udumula, V.; Smith, S. J.; Michaelis, D. J. Synthesis of N-Aryl “Hydroxylamines via Stalled Nitro Reductions with Soluble Ruthenium Nanoparticle Catalysts.” Tetrahedron Lett. 201758,82–86.


16. Udumula, V.; Nazari, S. H.; Burt, S. R.; Alfindee, M. N.; Michaelis, D. J. “Chemo- and Site-Selective Alkyl and Aryl Azide Reductions with Heterogeneous Nanoparticle Catalysts.” ACS Catal.20166, 4423–4427.


15. Talley, M. R.; Stokes, R. W.; Walker, W. K.; Michaelis, D. J. “Electrophilic Activation of Alkynes for Enyne Cycloisomerization Reactions with In Situ Generated Early/Late Heterobimetallic Pt–Ti Catalysts.” Dalton Trans. 201645, 9770–9773.    



14.  Walker, W. K.; Kay, B. M.; Michaelis, S. A.; Anderson, D. L.; Smith, S. J.; Ess, D. H.; Michaelis, D. J. “Origin of Fast Catalysis in Allylic Amination Reactions Catalyzed by Pd–Ti Heterobimetallic complexes.” J. Am. Chem. Soc. 2015, 137, 7371­–7378

                 pub 14

13. Udumula, V.; Tyler, J. H.; Davis, D. A.; Wang, H.; Linford, M. R.; Minson, P. S.; Michaelis, D. J. “A Dual Optimization Approach to Bimetallic Nanoparticle Catalysis: Impact of M1:M2 Ratio and Supporting Polymer Structure on Reactivity.” ACS Catal. 2015, 5, 3457–3462


12. Walker, W. K.; Anderson, D. L.; Stokes, R. W.; Smith, S. L.; Michaelis, D. J. “Allylic Aminations with Hindered Secondary Amine Nucleophiles Catalyzed by Heterobimetallic Ti–Pd Complexes.” Org. Lett. 2015, 17, 752–755.




Previous Publications

11. Williamson, K.S.; Michaelis, D.J.; Yoon, T.P. "Advances in the Chemistry of Oxaziridines," Chem. Rev. 2014114, 8016-8036.


10. Trost, B. M.; Michaelis, D. J.; Malhotra, S. “Total Synthesis of (–)-18-epi-peloruside A: An Alkyne Linchpin Strategy.” Org. Lett. 201315, 5274­–5277.


9. Trost, B. M.; Michaelis, D. J.; Truica, M. “Dinuclear Zinc–ProPhenol-Catalyzed Enantioselective α-Hydroxyacetate Aldol Reaction with Activated Ester Equivalents.” Org. Lett. 201315, 4516–4519. 


8. Trost, B. M.; Michaelis, D. J.; Charpentier, J.; Xu, J. “Palladium-catalyzed asymmetric allylic alkylation of carboxylic acid derivatives: N-acyloxazolinones as ester enolate equivalents.”  Angew. Chem. Int. Ed. 2012124, 208–112.


7. Trost, B. M.; Lehr, K.; Michaelis, D. J.; Xu, J.; Buckl, A. K. “Palladium-catalyzed asymmetric allylic alkylation of 2-acylimidazoles as ester enolate equivalents.” J. Am. Chem. Soc. 2010132, 8915–8917.


6. Michaelis, D. J.; Williamson, K. S.; Yoon, T. P. “Oxaziridine-mediated enantioselective aminohydroxylation of styrenes catalyzed by copper(II) bis(oxazoline) complexes.” Tetrahedron 200965, 5118–5124, invited symposium in print.


5. Michaelis, D. J.; Dineen, T. “Ring-opening of aziridines with o-halophenyllithium reagents: synthesis of 2-substituted chiral indolines.”  Tetrahedron Lett. 200950, 1920–1923.


4. Michaelis, D. J.; Ischay, M. A.; Yoon, T. P. “Activation of N-sulfonyl oxaziridines using copper(II) catalysts: aminohydroxylations of styrenes and 1,3-dienes.” J. Am. Chem. Soc. 2008130, 6610–6615.


3. Michaelis, D. J.; Shaffer, C. J.; Yoon, T. P. “Copper(II)-catalyzed aminohydroxylation of olefins.” J. Am. Chem. Soc. 2007129, 1866–1867.


2. Parent, A. A.; Anderson, T. M.; Michaelis, D. J.; Jiang, G.; Savage, P. B.; Linford, M. R. “Direct ToF-SIMS analysis of organic halides and amines on TLC plates.” Applied Surface Science 2006252, 6746–6749.


1. Bronson, R. T.; Michaelis, D. J.; Lamb, R. D.; Husseini, G. A.; Farnsworth, P. B.; Linford, M. R.; Izatt, R. M.; Bradshaw, J. S.; Savage, P. B. “Construction of a surface bound metal ion sensor for Cadmium.” Org. Lett. 20057, 1105–1108.