Chemistry and Biochemistry

BYU Researchers Find New Target for Pancreatic Cancer Treatment

Posted: Feb 08, 2019

One of the biggest challenges to cancer therapy is that cancer cells adapt to their environment and become resistant to treatment. New research by BYU professor John Price and grad student Monique Speirs found a way to slow this adaptation process — technically called metabolic reprogramming — in one of the most difficult cancers to treat: pancreatic cancer.

In a paper recently published in biomedical journal Oncotarget, Price and Speirs detail how targeting specific growth-regulating cell lipids can interrupt metabolic reprogramming in pancreatic cancer cells. The duo was able to successfully target the lipids by inhibiting certain enzymes responsible for their production. [Keep Reading]